• Clinically studied SPM Active supports the body's natural ability to resolve inflammation after strenuous physical exertion, helping recovery.
• The only SPM supplement with human clinical data showing proven improvements in joint comfort, sleep, and mood.
• Derived from fish oil (LIPINOVA) with 50 mg EPA and 100 mg DHA per softgel to support SPM activity and overall health.
• One softgel daily helps maintain tissue health and general wellbeing.
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Metagenics, SPM Active, 60 Softgels
Size
60
softgels
30 people have viewed this item in the last 7 days
About this item
Suggested Use
Adults and Adolescents (12-17) take 2 softgels once daily or as recommended by your healthcare practitioner.
Ingredients
Each softgel contains:
Fish Oil
500
mg
--Providing 50 mg EPA, 100 mg DHA (Derived from a blend of: sardine, anchovy, and mackerel)
Non-medical Ingredients:
Mixed tocopherols concentrate, softgel (gelatin, glycerin, water), and silica
Description
Specialized pro-resolving mediators (SPMs) are molecules our bodies produce naturally in response to damaged tissue due to physical challenges and are a critical component of the body’s natural healing process. Unfortunately, the body may not produce enough SPMs on its own. Diet, lifestyle, excess body fat, and other health challenges can affect SPM production. That’s where our clinically studied SPM Active can help.
Specialized pro-resolving mediators (SPMs) help promote resolution of physical stress after strenuous physical exertion. SPM Active® supports the body’s natural capacity to respond to physical challenges.
- The only SPM supplement with human clinical data with demonstrated results
- Helps promote tissue health
- Clinically demonstrated improvement in joint comfort, sleep, and mood
Frequently Asked Questions
What is Metagenics and who are its supplements designed for?
Metagenics is an American functional medicine supplement brand founded in 1983 by Dr. Jeffrey Bland, widely regarded as the father of functional medicine. Products address root causes of chronic illness rather than symptoms, targeting gut health, hormonal balance, detoxification, cardiometabolic health, and cognitive function. Manufacturing is USP GMP and NSF GMP certified, with over 60,000 quality control tests conducted annually. Metagenics is the number-one doctor-recommended professional supplement brand in North America and holds Certified B Corp status. Products are available through licensed healthcare practitioners.
What is Metagenics and are its supplements safe to use in Canada?
Metagenics is a science-based supplement brand founded in 1983, with Canadian operations headquartered in Mississauga, Ontario. All Metagenics products sold in Canada carry Health Canada Natural Product Numbers (NPN), confirming they have been reviewed for safety, efficacy, and quality under Canada's Natural Health Products Regulations. Manufacturing facilities are audited by USP GMP, NSF International GMP, and Canada's Natural and Non-Prescription Health Products Directorate (NNHPD). Metagenics is also a certified B Corporation (since 2022) and offers lot-level quality transparency through its TruQuality® Guarantee, allowing customers to verify testing results for every formula by lot number.
How is Metagenics different from regular supplement brands sold in stores?
Metagenics differs from typical retail supplements in three ways. First, it is a practitioner-grade brand — formulated for therapeutic use and traditionally distributed through licensed healthcare providers, not mass retail, making it the #1 Doctor Recommended Professional Supplement Brand in North America. Second, its formulas are built on nutrigenomics research — the science of how nutrition interacts with genes — backed by hundreds of clinical studies, with a focus on bioavailability-optimized ingredient forms rather than generic powders. Third, it maintains multi-layer independent quality verification: USP GMP, NSF GMP, and NNHPD Canada audits, with every formula's testing results accessible online by lot number via the TruQuality® Guarantee.
What makes Metagenics different from other professional-grade supplement brands?
Metagenics was built around nutrigenomics — the science of how nutrients regulate gene expression — a field its founder Dr. Jeffrey Bland helped pioneer before it was mainstream. This underpins formulas designed to modulate biological pathways at the cellular level, not just correct deficiencies. Unlike brands that adopted practitioner distribution as a later marketing channel, Metagenics was practitioner-exclusive from inception, with clinical protocols as the core of product design. It has participated in hundreds of clinical trials and conducts over 60,000 quality control tests annually — a depth of evidence unusual for the supplement category.
How Metagenics products tested for quality and safety?
Every Metagenics product undergoes rigorous testing at every stage of production, including raw ingredients, finished formulas, and final encapsulation. We don’t just meet industry standards—we exceed them.
While the FDA requires minimal oversight for supplements, we invest over $1.5 million annually into quality assurance. That includes nearly 50,000 tests per year conducted by more than 70 global quality experts to ensure purity, safety, and potency.
Each product is triple-tested for identity, strength, and consistency—so what’s on the label is exactly what’s in the bottle. And to hold ourselves to an even higher standard, we also voluntarily submit every product for third-party testing to confirm quality and transparency you can trust.
While the FDA requires minimal oversight for supplements, we invest over $1.5 million annually into quality assurance. That includes nearly 50,000 tests per year conducted by more than 70 global quality experts to ensure purity, safety, and potency.
Each product is triple-tested for identity, strength, and consistency—so what’s on the label is exactly what’s in the bottle. And to hold ourselves to an even higher standard, we also voluntarily submit every product for third-party testing to confirm quality and transparency you can trust.
The information provided above is for reference purposes only and has not been reviewed or approved by Health Canada. It does not constitute medical advice and should not replace consultation with a qualified healthcare professional.
Caution
Keep tightly closed in a cool, dry place. Do not use if perma seal is missing.
Disclaimer
You should not use the information or services on this Site to diagnose or treat any health issues or for prescription of any medication or other treatment.
Always check the product label or packaging prior to using any product. If there are discrepancies, customers should follow the information provided on the product label or packaging.
Metagenics, SPM Active, 60 Softgels
Size
60
softgels
30 people have viewed this item in the last 7 days
$82.50
Quantity
Not enough inventory in stock
Purchase limit exceeded
In-Store Purchases
Not available for immediate pickup
You can order online and pickup in store.
Free in-store pickup available
Ready by
Thursday, May 28
⏱️
Shipping Options
Available to ship
Estimate Ship Date
Thursday, May 28
⏱️
Metro Vancouver
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Within Canada
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United States
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Note
Due to the nature of this item, we cannot accept any returns.
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