Do not use if you have liver or kidney disorders, or are pregnant or breastfeeding. Do not drive or operate heavy machinery for 5 hours after taking melatonin. Consult a healthcare practitioner prior to use if you suffer from epilepsy, or have cardiovascular, immune, hormonal or seizure disorders, asthma, depression, diabetes, low blood sugar, or migraine. Consult a healthcare practitioner prior to use if you are taking medications for seizure, blood pressure, to suppress immune system (immunosuppressive medications), to affect mental state or increase sedation, steroids, blood thinners, conventional sedative hypnotics, (or natural health products with similar effects), antipsychotics, MAO inhibitors, other psycho-pharmacological agents, levodopa (or other drugs for Parkinson’s disease) or antithrombotics. Stop use if allergy occurs or if you experience headache, confusion, or nausea. Discontinue use and consult a healthcare practitioner if you develop symptoms of liver trouble, such as yellowing of the skin/eyes (jaundice), stomach pain, dark urine, sweating, nausea unusual tiredness and/or loss of appetite. Hypersensitivity is known to occur, in which case discontinue use. Consumption with alcohol, products that cause drowsiness, or anti-convulsants is not recommended. Consult a healthcare practitioner for use is not recommended. Consult a healthcare practitioner for use beyond 4 weeks or if sleeplessness persists continuously for beyond 4 weeks or if sleeplessness persists continuously for more than 4 weeks or if symptoms persist or worsen.