• Metagenics Lipo-Gen blends lipotropic nutrients with key amino acids, vitamins, and a proprietary herbal extract to support healthy liver and gallbladder function.
• It promotes fat metabolism and supports fatty liver health with ingredients like choline, inositol, L-methionine, betaine HCl, and chen pi 5:1 extract.
• Artichoke leaf extract further supports bile production and digestive comfort.
• A 90-tablet supply from Metagenics delivers essential vitamins (C, B6, B12, folate) and magnesium to support metabolic health and daily wellness.
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Metagenics, Lipo-Gen™, 90 Tablets
Size
90
tablets
UPC
755571919915
Best Before
10/2027
32 people have viewed this item in the last 7 days
About this item
Suggested Use
Adults take 2 tablets daily at mealtime or as directed by your healthcare practitioner.
Ingredients
Each tablet contains:
Choline (choline bitartrate)
150
mg
Inositol
75
mg
Vitamin C (ascorbic acid)
50
mg
Taurine
50
mcg
L-Methionine
50
mg
Betaine HCl
50
mg
Chen Pi (Citrus reticulata) 5:1 fruit extract equivalent to 162.5 mg of Chen Pi
32.5
mg
Magnesium (magnesium oxide)
25
mg
Artichoke (Cynara scolymus L) 10:1 leaf equivalent to 150 mg of artichoke
15
mg
Vitamin B6 (pyridoxine HCl)
5
mg
Folate (calcium L-5-methyltetrahydrofolate)
50
mcg
Vitamin B12 (methylcobalamin)
5
mcg
Non-medical Ingredients:
Cellulose, stearic acid (veg), croscarmellose sodium, silicon dioxide, and coating (hypromellose, hydroxypropylcellulose, and medium-chain triglycerides).
Description
Lipo-Gen™ is a highly specialized formula that features a unique blend of lipotropic nutrients combined with select amino acids, vitamins, and a proprietary extract of herbs to support healthy liver and gallbladder function.
Frequently Asked Questions
What is Metagenics Lipo-Gen and what is it used for?
Metagenics Lipo-Gen is a lipotropic formula combining choline, inositol, L-methionine, and betaine HCl with artichoke extract, tangerine peel, and active-form B vitamins (methylfolate and methylcobalamin B12). It is designed to support healthy liver fat metabolism, reduce hepatic fat accumulation, and promote bile production and gallbladder function -- particularly relevant for adults managing fatty liver (NAFLD/NASH), elevated triglycerides, or impaired hepatic detoxification pathways.
What are the key ingredients in Lipo-Gen and how do they work?
Each tablet provides choline bitartrate (150 mg), inositol (75 mg), L-methionine (50 mg), betaine HCl (50 mg), tangerine peel 5:1 extract (32.5 mg), magnesium oxide (25 mg), artichoke leaf 10:1 extract (15 mg), vitamin B6 (5 mg), L-5-methyltetrahydrofolate methylfolate (50 mcg), and methylcobalamin B12 (5 mcg). Choline, methionine, and betaine are lipotropic agents supporting phosphatidylcholine synthesis required for VLDL assembly -- the mechanism that exports triglycerides from the liver. Without adequate lipotropic support, liver fat accumulates. Artichoke extract acts as a choleretic, stimulating bile production to support fat digestion and gallbladder drainage. Methylfolate and methylcobalamin are active B-vitamin forms supporting homocysteine metabolism.
Who should take Lipo-Gen and who should avoid it?
Lipo-Gen is suited for adults seeking nutritional support for liver fat metabolism, gallbladder function, or elevated triglycerides -- particularly those with non-alcoholic fatty liver, sluggish bile flow, or a long history of high-fat diet. Take 2 tablets daily with meals, or as directed by a healthcare provider. Do not use if you have bile duct obstruction or are allergic to plants in the Asteraceae (artichoke/daisy) family. Use with caution if pregnant or if you have gallstones -- consult a physician before use. If using for more than 12 weeks, physician supervision is recommended.
What distinguishes Metagenics Lipo-Gen from other liver support supplements?
Lipo-Gen integrates four complementary lipotropic mechanisms in a single formula: phospholipid synthesis support (choline + inositol + methionine), methyl-donor recycling (betaine HCl supporting the choline-methionine-SAM cycle), choleretic bile stimulation (artichoke 10:1 extract), and homocysteine metabolism (methylfolate + methylcobalamin -- active B-vitamin forms rather than synthetic folic acid and cyanocobalamin). Most liver supplements address only one or two of these pathways. The use of L-5-methyltetrahydrofolate (methylfolate) and methylcobalamin also makes the formula suitable for people with MTHFR gene variants who cannot efficiently convert standard folic acid.
What is Metagenics and who are its supplements designed for?
Metagenics is an American functional medicine supplement brand founded in 1983 by Dr. Jeffrey Bland, widely regarded as the father of functional medicine. Products address root causes of chronic illness rather than symptoms, targeting gut health, hormonal balance, detoxification, cardiometabolic health, and cognitive function. Manufacturing is USP GMP and NSF GMP certified, with over 60,000 quality control tests conducted annually. Metagenics is the number-one doctor-recommended professional supplement brand in North America and holds Certified B Corp status. Products are available through licensed healthcare practitioners.
What is Metagenics and are its supplements safe to use in Canada?
Metagenics is a science-based supplement brand founded in 1983, with Canadian operations headquartered in Mississauga, Ontario. All Metagenics products sold in Canada carry Health Canada Natural Product Numbers (NPN), confirming they have been reviewed for safety, efficacy, and quality under Canada's Natural Health Products Regulations. Manufacturing facilities are audited by USP GMP, NSF International GMP, and Canada's Natural and Non-Prescription Health Products Directorate (NNHPD). Metagenics is also a certified B Corporation (since 2022) and offers lot-level quality transparency through its TruQuality® Guarantee, allowing customers to verify testing results for every formula by lot number.
How is Metagenics different from regular supplement brands sold in stores?
Metagenics differs from typical retail supplements in three ways. First, it is a practitioner-grade brand — formulated for therapeutic use and traditionally distributed through licensed healthcare providers, not mass retail, making it the #1 Doctor Recommended Professional Supplement Brand in North America. Second, its formulas are built on nutrigenomics research — the science of how nutrition interacts with genes — backed by hundreds of clinical studies, with a focus on bioavailability-optimized ingredient forms rather than generic powders. Third, it maintains multi-layer independent quality verification: USP GMP, NSF GMP, and NNHPD Canada audits, with every formula's testing results accessible online by lot number via the TruQuality® Guarantee.
What makes Metagenics different from other professional-grade supplement brands?
Metagenics was built around nutrigenomics — the science of how nutrients regulate gene expression — a field its founder Dr. Jeffrey Bland helped pioneer before it was mainstream. This underpins formulas designed to modulate biological pathways at the cellular level, not just correct deficiencies. Unlike brands that adopted practitioner distribution as a later marketing channel, Metagenics was practitioner-exclusive from inception, with clinical protocols as the core of product design. It has participated in hundreds of clinical trials and conducts over 60,000 quality control tests annually — a depth of evidence unusual for the supplement category.
How Metagenics products tested for quality and safety?
Every Metagenics product undergoes rigorous testing at every stage of production, including raw ingredients, finished formulas, and final encapsulation. We don’t just meet industry standards—we exceed them.
While the FDA requires minimal oversight for supplements, we invest over $1.5 million annually into quality assurance. That includes nearly 50,000 tests per year conducted by more than 70 global quality experts to ensure purity, safety, and potency.
Each product is triple-tested for identity, strength, and consistency—so what’s on the label is exactly what’s in the bottle. And to hold ourselves to an even higher standard, we also voluntarily submit every product for third-party testing to confirm quality and transparency you can trust.
While the FDA requires minimal oversight for supplements, we invest over $1.5 million annually into quality assurance. That includes nearly 50,000 tests per year conducted by more than 70 global quality experts to ensure purity, safety, and potency.
Each product is triple-tested for identity, strength, and consistency—so what’s on the label is exactly what’s in the bottle. And to hold ourselves to an even higher standard, we also voluntarily submit every product for third-party testing to confirm quality and transparency you can trust.
The information provided above is for reference purposes only and has not been reviewed or approved by Health Canada. It does not constitute medical advice and should not replace consultation with a qualified healthcare professional.
Caution
Do not use if you have a bile duct obstruction or are allergic to plants of the Asteraceae/Compositae/Daisy family. Hypersensitivity (e.g. allergy) has been known to occur; in which case, discontinue use. Consult a healthcare practitioner prior to use if you are pregnant, or have gallstones, or if symptoms persist or worsen. Consult a healthcare practitioner for use beyond 12 weeks. Do not use if perma seal is missing.
Disclaimer
You should not use the information or services on this Site to diagnose or treat any health issues or for prescription of any medication or other treatment.
Always check the product label or packaging prior to using any product. If there are discrepancies, customers should follow the information provided on the product label or packaging.
Metagenics, Lipo-Gen™, 90 Tablets
Size
90
tablets
UPC
755571919915
Best Before
10/2027
32 people have viewed this item in the last 7 days
$42.50
Quantity
Not enough inventory in stock
Purchase limit exceeded
In-Store Purchases
In stock at LIFEPLUS Natural Health
#1825 - 4720 Mcclelland Rd, Richmond, BC
Free in-store pickup available
Ready by
Today, Jun 22
⏱️
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