• Clinically effective levels of SAMe, paired with body-ready folate and methylcobalamin B12, support a healthy mood and balanced neurotransmitter synthesis. This combination also promotes SAMe metabolism and methylation for ongoing emotional well-being.
• Enteric-coated, foil-wrapped tablets protect the formula and help ensure stable, reliable absorption with each dose.
• The blend targets methylation pathways to support positive mood and overall emotional balance.
• Convenient 30-tablet supply from Metagenics provides consistent daily support for mood health.
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Metagenics, Blisphora, 30 Tablets
Size
30
tablets
UPC
755571936264
24 people have viewed this item in the last 7 days
About this item
Suggested Use
Adults take 1 tablet per day on an empty stomach with water 30 minutes before a meal or as directed by your healthcare practitioner.
Ingredients
Each tablet contains:
S-Adenosylmethionine (SAMe)
400
mg
Folate [(6S)-5-Methyltetrahydrofolic acid, glucosamine salt]
1000
mcg
Vitamin B12 (methylcobalamin)
1000
mcg
Non-medical Ingredients:
Cellulose, magnesium stearate (veg), stearic acid (veg), silicon dioxide, mannitol, sodium carboxymethyl starch, and coating (methacrylic acid copolymer, triethyl citrate, titanium dioxide, and silicon dioxide).
Description
Blisphora® is a revolutionary formula featuring clinically effective levels of SAMe (s-adenosyl-L-methionine), a compound native to the body that is a critical component of many biochemical reactions and plays an important role in supporting positive emotions. This powerful formula combines significant levels of body-ready folate (the next generation of folate with improved bioavailability) and vitamin B12 (as easy-to-absorb methylcobalamin) to support SAMe metabolism, methylation, and healthy neurotransmitter synthesis for a balanced mood. Foil-wrapped, enteric-coated tablets ensure product stability.
- Scientifically designed to support a healthy mood and methylation
- Features clinically effective levels of SAMe and body-ready folate and vitamin B12
Frequently Asked Questions
What is Metagenics and are its supplements safe to use in Canada?
Metagenics is a science-based supplement brand founded in 1983, with Canadian operations headquartered in Mississauga, Ontario. All Metagenics products sold in Canada carry Health Canada Natural Product Numbers (NPN), confirming they have been reviewed for safety, efficacy, and quality under Canada's Natural Health Products Regulations. Manufacturing facilities are audited by USP GMP, NSF International GMP, and Canada's Natural and Non-Prescription Health Products Directorate (NNHPD). Metagenics is also a certified B Corporation (since 2022) and offers lot-level quality transparency through its TruQuality® Guarantee, allowing customers to verify testing results for every formula by lot number.
How is Metagenics different from regular supplement brands sold in stores?
Metagenics differs from typical retail supplements in three ways. First, it is a practitioner-grade brand — formulated for therapeutic use and traditionally distributed through licensed healthcare providers, not mass retail, making it the #1 Doctor Recommended Professional Supplement Brand in North America. Second, its formulas are built on nutrigenomics research — the science of how nutrition interacts with genes — backed by hundreds of clinical studies, with a focus on bioavailability-optimized ingredient forms rather than generic powders. Third, it maintains multi-layer independent quality verification: USP GMP, NSF GMP, and NNHPD Canada audits, with every formula's testing results accessible online by lot number via the TruQuality® Guarantee.
How Metagenics products tested for quality and safety?
Every Metagenics product undergoes rigorous testing at every stage of production, including raw ingredients, finished formulas, and final encapsulation. We don’t just meet industry standards—we exceed them.
While the FDA requires minimal oversight for supplements, we invest over $1.5 million annually into quality assurance. That includes nearly 50,000 tests per year conducted by more than 70 global quality experts to ensure purity, safety, and potency.
Each product is triple-tested for identity, strength, and consistency—so what’s on the label is exactly what’s in the bottle. And to hold ourselves to an even higher standard, we also voluntarily submit every product for third-party testing to confirm quality and transparency you can trust.
While the FDA requires minimal oversight for supplements, we invest over $1.5 million annually into quality assurance. That includes nearly 50,000 tests per year conducted by more than 70 global quality experts to ensure purity, safety, and potency.
Each product is triple-tested for identity, strength, and consistency—so what’s on the label is exactly what’s in the bottle. And to hold ourselves to an even higher standard, we also voluntarily submit every product for third-party testing to confirm quality and transparency you can trust.
The information provided above is for reference purposes only and has not been reviewed or approved by Health Canada. It does not constitute medical advice and should not replace consultation with a qualified healthcare professional.
Caution
Do not use if you are pregnant, breastfeeding, or have hyperhomocysteinemia. Do not take at night since product may cause anxiety, restlessness and insomnia. Not recommended for use in children. If taking anti-depressant medications, hepatoxic drugs or monoamine oxidase (MAO) inhibitors, consult your healthcare practitioner before taking SAMe in place of or in addition to those medications. Possible side effects are: mild gastrointestinal upsets (such as stomach pain, nausea, diarrhea, and flatulence), anxiety, hyperactive muscle movement, insomnia, and hypomania. People with bipolar disorder (manic-depressive illness) should not use SAMe unless under medical supervision. For prolonged use or if symptoms persist, consult a healthcare practitioner. Do not use if package is torn or open.
Disclaimer
You should not use the information or services on this Site to diagnose or treat any health issues or for prescription of any medication or other treatment.
Always check the product label or packaging prior to using any product. If there are discrepancies, customers should follow the information provided on the product label or packaging.
Metagenics, Blisphora, 30 Tablets
Size
30
tablets
UPC
755571936264
24 people have viewed this item in the last 7 days
$81.50
Quantity
Not enough inventory in stock
Purchase limit exceeded
In-Store Purchases
Not available for immediate pickup
You can order online and pickup in store.
Free in-store pickup available
Ready by
Wednesday, May 20
⏱️
Shipping Options
Available to ship
Estimate Ship Date
Wednesday, May 20
⏱️
Metro Vancouver
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Within Canada
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United States
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Note
Due to the nature of this item, we cannot accept any returns.
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