What is AOR Nattokinase, and what is it used for?
AOR Nattokinase is a cardiovascular enzyme supplement providing 100 mg of nattokinase per vegetarian capsule, standardized to 2,000–2,800 fibrinolytic units (FU), derived from fermented non-GMO soybean extract, licensed under Health Canada NPN 80089368. Nattokinase is a serine protease produced during traditional natto fermentation (Bacillus subtilis) that supports healthy blood flow by promoting the natural breakdown of fibrin — the protein that forms blood clots — and by helping prevent new clot formation. It is used for cardiovascular health maintenance, blood viscosity management, and circulatory support. Adults take 1 vegetarian capsule daily with a meal.
What are the ingredients in AOR Nattokinase and what does each do?
The active ingredient is nattokinase (100 mg, 2,000–2,800 FU) from fermented non-GMO soybean extract. FU (fibrinolytic units) is the standardized measure of the enzyme's clot-dissolving activity, ensuring consistent potency across batches. Excipients include microcrystalline cellulose, beta-cyclodextrin, maltodextrin, and hydroxypropyl methylcellulose (HPMC, vegetable capsule shell). Important: this product contains soy and corn derivatives — individuals with soy or corn allergies should not use it.
Who should take AOR Nattokinase, and how is it used?
Suitable for healthy or at-risk adults seeking to maintain cardiovascular health, normal blood circulation, and healthy blood viscosity. Take 1 vegetarian capsule daily with a meal. This product must not be used by people who are pregnant or breastfeeding, taking blood-thinning medications (e.g., warfarin, aspirin, clopidogrel), or who have bleeding disorders, liver disease, or kidney disease. Discontinue use at least 7 days before any planned surgery. Seek immediate medical attention if unexpected bruising or bleeding occurs.
How does AOR Nattokinase stand out compared to other nattokinase products?
AOR's nattokinase is standardized to 2,000–2,800 FU per 100 mg capsule — the minimum 2,000 FU aligns with the Japan Health and Nutrition Foods Association (JHFA) recommended daily intake for cardiovascular maintenance in healthy individuals. Many generic nattokinase products disclose dosage in mg only, without FU standardization, making it impossible to verify actual enzymatic activity. A large clinical study published in Frontiers in Cardiovascular Medicine (2022, n=1,062 participants) confirmed nattokinase's efficacy in managing atherosclerosis progression and improving lipid profiles; a 2024 systematic review and meta-analysis of RCTs further supports cardiovascular benefits. The non-GMO fermented soy source and vegetarian capsule format also make this product accessible to vegetarians.
What is AOR (Advanced Orthomolecular Research) and are its supplements safe in Canada?
AOR, short for Advanced Orthomolecular Research, is a Calgary, Alberta-based supplement brand founded in 1991 by Dr. Traj Nibber, PhD. Built on the orthomolecular medicine principles of Nobel laureate Linus Pauling — the right molecule, in the right dose, at the right place and time — AOR products are manufactured in a cGMP-compliant facility in Alberta and all carry Health Canada Natural Product Numbers (NPN). Raw materials are independently tested in ISO-certified laboratories for purity, potency, and safety. Products are commonly recommended by naturopathic doctors and integrative healthcare practitioners across Canada.
What makes AOR different from other supplement brands?
AOR's real distinction is its orthomolecular research model: rather than formulating to meet basic RDAs, AOR targets functional, clinically studied dosing levels — and has a track record of introducing compounds to the Canadian market before they became mainstream, including D-ribose, R-lipoic acid, and strontium citrate. AOR also consistently chooses bioavailable ingredient forms over cheaper alternatives: methylated B vitamins (methylcobalamin, L-5-MTHF) instead of cyanocobalamin; chelated magnesium bisglycinate instead of magnesium oxide. This research-first approach, developed in close collaboration with naturopathic doctors, is what separates AOR from brands that replicate popular formulas at lower cost.
The information provided above is for reference purposes only and has not been reviewed or approved by Health Canada. It does not constitute medical advice and should not replace consultation with a qualified healthcare professional.