• Supports cardiovascular health by aiding fibrinolysis. Nattokinase helps break down fibrin to promote healthy blood flow.
• Each daily capsule delivers 2000 FU of NSK-SD nattokinase (100 mg), a patented, highly purified form used in clinical studies.
• Made from non-GMO soybeans with vitamin K2 removed to avoid medication interactions.
• 60 vegetarian capsules provide a convenient daily dose.
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Natural Factors, Nattokinase, 2000FU/100mg, 60 VCaps
Size
60
vegetarian capsules
UPC
627765017250
Best Before
03/2030
120 people have viewed this item in the last 7 days
About this item
Suggested Use
Recommended adult dose: 1 capsule daily or as directed by a health care practitioner. Consult a health care practitioner for use beyond 4 weeks.
Ingredients
Each vegetarian capsule contains:
Nattokinase (fermented soy extract, Glycine max – seed 2000 FU)
100
mg
Non-medical Ingredients:
Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.
Description
Natural Factors Nattokinase is a fibrinolytic enzyme derived from whole natto concentrate to help support cardiovascular health. Natto is a traditional Japanese food made from fermented soybeans and is widely recognized for its health benefits. This formula features NSK-SD®, a patented and highly purified form of nattokinase used in multiple clinical studies. It is made using non-GMO soybeans and has the naturally occurring vitamin K2 removed to avoid interactions with certain medications.
- Helps support cardiovascular health
- Contains nattokinase, an enzyme from naturally fermented, non-GMO soybeans
- Features the patented NSK-SD form of nattokinase used in clinical studies
- Contains no vitamin K2
- Provides 2000 FU (fibrinolytic units) of nattokinase in each daily capsule
Frequently Asked Questions
What is Natural Factors Nattokinase, and what is nattokinase?
Natural Factors Nattokinase provides 100 mg of NSK-SD nattokinase per vegetarian capsule, delivering 2,000 fibrinolytic units (FU) — the standardized activity measure for nattokinase. Nattokinase is a serine protease enzyme produced during the fermentation of soybeans by Bacillus subtilis natto, the same process used to make natto, a traditional Japanese food. The enzyme has potent fibrinolytic activity, meaning it breaks down fibrin — the protein mesh that forms blood clots. In Japan, Korea, and China, nattokinase has been widely used for cardiovascular health, and it has gained recognition in Western functional medicine for its ability to support healthy blood flow, reduce the risk of clot formation, and support overall vascular health without the bleeding side effects associated with pharmaceutical blood thinners.
How does nattokinase support cardiovascular health, and what does the evidence show?
Nattokinase works through multiple complementary cardiovascular mechanisms. It directly degrades fibrin in existing clots, enhancing the body's natural thrombolytic capacity without producing the same bleeding risk as aspirin or anticoagulant medications. It inhibits thromboxane synthesis, reducing platelet aggregation and the tendency for new clot formation. Research also suggests it supports blood pressure reduction by inhibiting angiotensin-converting enzyme (ACE), similar to the mechanism of ACE inhibitor drugs. Beyond blood flow, nattokinase has demonstrated benefits for conditions associated with venous stasis including hemorrhoids and varicose veins, and may help slow atherosclerotic plaque progression. The NSK-SD form used in this product is purified to remove naturally occurring vitamin K2 — which is present in natto food but can interfere with anticoagulant medications like warfarin — making it a safer choice for individuals with cardiovascular drug protocols.
Who is nattokinase suitable for, and what are the important precautions?
Nattokinase is suitable for adults seeking natural cardiovascular support — particularly those with a personal or family history of high blood pressure, elevated clotting risk, atherosclerosis, poor circulation, or venous conditions such as varicose veins or hemorrhoids. It is also used by individuals who have been advised to reduce blood viscosity but prefer to avoid pharmaceutical blood thinners. The recommended adult dose is one capsule daily. Important precautions: do not use if pregnant or breastfeeding; do not use if allergic to soy products; do not use if taking blood-thinning medications without physician supervision; stop use at least 7 days before any surgical procedure; discontinue immediately if unplanned injury, bruising, or bleeding occurs; and consult a physician before use if you have cardiovascular, kidney, or liver disease.
What makes Natural Factors Nattokinase different from other nattokinase products, and why does the NSK-SD form matter?
Natural Factors Nattokinase uses the NSK-SD patented form of nattokinase, which is specifically differentiated by two properties: it is produced from non-GMO soybeans, and vitamin K2 has been deliberately removed during purification. This distinction is clinically important because vitamin K2 in regular natto food promotes clot formation — the opposite of the desired cardiovascular effect — and can potentiate the action of anticoagulant drugs. Most generic nattokinase products on the market do not specify whether vitamin K2 has been removed, making their safety profile less clear for individuals on cardiovascular medications. NSK-SD is the form used in published human clinical trials on nattokinase, which adds direct evidence relevance to the ingredient. Natural Factors also applies its ISURA third-party testing standard and four-round quality verification to this product, ensuring the labeled 2,000 FU activity and 100 mg content are verified at time of use.
What is Natural Factors, and is it a trustworthy supplement brand?
Natural Factors is a Canadian-owned supplement manufacturer founded in 1948 and headquartered in Coquitlam, British Columbia. One of North America's largest supplement makers, it operates over 1,000 acres of certified organic farmland in BC's Okanagan Valley and manufactures in-house at Health Canada-licensed, FDA-inspected facilities. Every product is third-party tested through ISURA for over 800 contaminants including pesticides and heavy metals. Natural Factors is also B Corp certified, meeting rigorous environmental and social standards.
What is Natural Factors and is it a reliable Canadian supplement brand?
Natural Factors is one of Canada's largest supplement manufacturers, founded in 1955 by Jack and Rona Katz in British Columbia and still 100% Canadian family-owned. The company controls every production stage from raw material sourcing to finished product. Its facility holds TGA certification from Australia's Therapeutic Goods Administration, one of the world's strictest supplement manufacturing standards. All products are ISURA certified — independently tested for 800+ contaminants including pesticides and heavy metals — and Natural Factors conducts four rounds of product testing, double the industry average of two.
What sets Natural Factors apart from other supplement brands?
Natural Factors' most distinctive quality is vertical integration: the company grows its own raw herbs on 1,000+ acres of certified organic farmland in BC's Okanagan Valley, then processes and manufactures in-house. Most supplement brands source raw materials from external suppliers with no direct agricultural control. Natural Factors also uses ISURA third-party testing, a Canadian standard that screens for over 800 contaminants, well beyond typical heavy-metal panels. B Corp certification further reflects a documented commitment to environmental and social accountability, not just a marketing claim.
What makes Natural Factors different from other Canadian supplement manufacturers?
Natural Factors holds TGA certification from Australia's Therapeutic Goods Administration — one of the world's most rigorous pharmaceutical manufacturing standards, rarely earned by Canadian brands and far exceeding most North American certification requirements. Its ISURA testing program screens every product for 800+ contaminants, and it conducts four rounds of quality testing per product versus the industry standard of two. The company also operates its own farm in the Okanagan Valley for select botanical ingredients — a level of vertical integration uncommon among supplement manufacturers — and has been family-owned for over 70 years.
The information provided above is for reference purposes only and has not been reviewed or approved by Health Canada. It does not constitute medical advice and should not replace consultation with a qualified healthcare professional.
Caution
This product is derived from soy. Do not use if you have soy allergy. Do not use if you are pregnant or breastfeeding, if you are taking health products that affect blood coagulation, or if you have a bleeding disorder. Stop using this product 7 days before any scheduled surgery, or immediately if you have unscheduled surgery or if you suffer from an injury resulting in bruising or bleeding. Consult a health care practitioner if you have a cardiovascular, kidney, or liver disorder, or if you are taking any medications. Keep out of the reach of children.
Disclaimer
You should not use the information or services on this Site to diagnose or treat any health issues or for prescription of any medication or other treatment.
Always check the product label or packaging prior to using any product. If there are discrepancies, customers should follow the information provided on the product label or packaging.
Natural Factors, Nattokinase, 2000FU/100mg, 60 VCaps
Size
60
vegetarian capsules
UPC
627765017250
Best Before
03/2030
120 people have viewed this item in the last 7 days
$23.99
Quantity
Not enough inventory in stock
Purchase limit exceeded
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In stock at LIFEPLUS Natural Health
#1825 - 4720 Mcclelland Rd, Richmond, BC
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