Designs for Health, B-Supreme, 60 Vegetarian Capsules

B-Supreme by Designs for Health is a comprehensive B vitamin complex formula designed to promote micronutrient status for optimal cellular function and healthy physiology. It supplies clinically useful amounts of B vitamins in their preferred coenzymated and phosphorylated forms where possible to be used in biochemical reactions more readily and easily. B-Supreme contains the bioidentical and methylated forms of folate and vitamin B12 for superior bioavailability. Choline and trimethylglycine (TMG) are added to help support efficient methylation for optimal genetic expression.

HIGHLIGHTS

• Formulated with bioidentical and coenzymated forms of B vitamins for enhanced absorption and bioavailability.
• Features the bioactive form of folate, as Quatrefolic® [6S]-5-methyltetrahydrofolate (MTHF), and vitamin B12, as MecobalActive® methylcobalamin.
• Choline and TMG added to support methylation pathways.
• Vegetable capsule; suitable for vegetarians and vegans.

B vitamins are a family of eight water-soluble micronutrients that are needed in small amounts by the body. B vitamins fall into two main categories: (1) those involved in the transfer of single-carbon atoms (i.e., one-carbon metabolism), and (2) those involved in the enzymatic reactions related to energy production and redox status. High-risk populations for B vitamin deficiencies include vegans and vegetarians, alcoholics, patients with congestive heart failure, obesity, and diabetes, the elderly, and individuals who have had bariatric surgery.

Supplementation with B complex vitamins has been shown to reduce homocysteine (Hcy) levels (an inflammatory marker in cardiovascular, metabolic, and neurological conditions), slow the rate of cognitive decline, and exhibit analgesic properties by activating the nitric oxide/cyclic guanosine monophosphate (cGMP) pathway.

The levels of vitamins B2, B6, B12, and folate found in B-Supreme are adequate for maintaining healthy Hcy levels for a large section of the population, but not for those with single nucleotide polymorphisms (SNP) in the Hcy metabolic pathways and/or folate receptor activity. The GenomicInsight™ report by Diagnostic Solutions Laboratory identifies which nutrients are required in higher doses to normalize Hcy within the body. This test is relevant to both the maternal and paternal genomic profiles, considering that the offspring inherit a combination of both.